Download Appleton & Lange Review of Pediatrics (Appleton & Lange by Sara Viessman PDF

By Sara Viessman

I used this e-book as a first-rate source for my third yr shelf examination (with Blueprints as a fall-back), and that i obtained a 4.0. I observed a few questions and eventualities at the try that I recogized from this article.

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1 Prevention: Primary and Secondary . . 2 Interventions . . . . . . . . 6 Future Directions . . . . . . . . References . . . . . . . . . . . . . . . . . . . . 35 35 35 36 37 39 39 40 . . . . . . 1 Introduction Treatment for childhood cancer can result in damaging effects on the central nervous system (CNS). The spectrum of potential toxicities includes paralysis, neuropathies, blindness, and seizures. Furthermore, survivors may experience decline in intellectual function, learning problems, behavior disorders, school failure, and impaired employability.

Somnolence and other acute CNS changes may be dose-limiting for this new agent [59]. It is too early to know the long-term effects. Subacute effects of radiation therapy (those occurring within the first 6 months of exposure) are more common than acute effects. One of the most common of these, the somnolence syndrome, has been described as occurring in up to 50% of children who receive radiation as CNS prophylaxis for acute lymphoblastic leukemia. The syndrome presents with fatigue, somnolence, anorexia, and nausea typically occurring 4–8 weeks after the completion of radiation therapy [60].

2 Disease Considerations . . . . . 3 Radiation. . . . . . . . . 4 Intrathecal Chemotherapy . . . . 5 Systemic Chemotherapy . . . . . 3 Clinical Presentations . . . . . . . 4 Moderators and Mediators of Central Nervous System Outcomes . . . 5 Prevention and Intervention . . . . . 1 Prevention: Primary and Secondary . . 2 Interventions . . . . . . . . 6 Future Directions . . . . . . . . References . . . . . . . . . . . . . . . .

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